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Die neuronalenTorres-Krperchen bei der experimentellen Gelbfieber-Encephalomyelitis: Ein weiteres Beispiel fr die uneinheitliche Natur der Kerneinschlsse vom Typ A nach Cowdry by Karl Blinzinger; Susanne Luh; Archinto P. Anzil is a Medicine article available to read on EtoBox.

What is Die neuronalenTorres-Krperchen bei der experimentellen Gelbfieber-Encephalomyelitis: Ein weiteres Beispiel fr die uneinheitliche Natur der Kerneinschlsse vom Typ A nach Cowdry about?

In experimental yellow fever virus encephalomyelitis of adult albino mice, the occurrence of intranuclear inclusions within nerve cells, in particular, within spinal and bulbar motoneurons, is a constant finding. The light microscopic features of these so-called neuronal Torres bodies correspond entirely to the criteria laid down by Cowdry for the type A intranuclear inclusions. At the ultrastructural level, these karyoplasmic formations consist of haphazardly distributed patches of an essentially amorphous material of various density. Unlike the Cowdry type A intranuclear inclusions characteristic of several herpesvirus and paramyxovirus infections, neuronal Torr-s bodies do not contain any viral structures. The frequency with which neuronal Torres bodies, certain nucleolar alterations and severe tigrolytic changes occur together, possibly indicates that this sort of type A intranuclear inclusion developes as a consequence of a virus induced disturbance of the cell nucleic acid and/or protein anabolism.

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Author

Karl Blinzinger; Susanne Luh; Archinto P. Anzil

Publisher

Springer-Verlag; Dr. Dietrich Steinkopff Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1433-8491)

Published

1976

Language

DE

Field

Medicine (Health Sciences)