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What is Single-Cell DNA Replication Timing Insights about?

This review discusses the regulation of DNA replication timing in mammalian cells, highlighting its correlation with transcription, chromatin structure, and genome organization. Recent advancements in single-cell DNA replication profiling have confirmed that megabase-sized replication domains are preserved at the single-cell level, allowing for a deeper understanding of genome regulation. The article outlines the historical context, key findings, and future directions for research in this area, emphasizing

Author

TATIANA LUCIA DIAZ HUERTA

Language

EN