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Vitiligo and overt thyroid diseases: A nationwide population-based study in Korea by Jung Min Bae; June Hyunkyung Lee; Jae Seung Yun; Byeol Han; Tae Young Han is a Medicine article available to read on EtoBox.

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## Background: Associations between vitiligo and thyroid diseases have been reported repeatedly. ## Objective: We investigated the associations between vitiligo and overt autoimmune thyroid diseases and thyroid cancer using the korean national health insurance claims database. ## Methods: We defined patients with vitiligo as those whose records showed ≥4 physician contacts between 2009 and 2013 in which vitiligo was the principal diagnosis. we also established an age- and sex-matched control group without vitiligo (2 per 1 vitiligo patient). the outcomes of interest were concurrent graves disease and hashimoto thyroiditis (the patients were taking relevant thyroid medications) and thyroid cancer. ## Results: The study enrolled 73,336 vitiligo patients and 146,672 controls. patients with vitiligo were at increased risks of graves disease (odds ratio [or] 2.610 [95% confidence interval {ci} 2.319-02.938]), hashimoto thyroiditis (or 1.609 [95% ci 1.437-1.802]), and thyroid cancer (or 1.127 [95% ci 1.022-1.242]), compared with the controls. the associations were consistently stronger in males and younger patients. ## Limitations: Individual clinical information was not available, and t

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Author

Jung Min Bae; June Hyunkyung Lee; Jae Seung Yun; Byeol Han; Tae Young Han

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Medicine (Health Sciences)