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Improved focal liver lesion detection: Comparison of single-shot spin-echo echo-planar and superparamagnetic iron oxide (SPIO)-enhanced MRI by Kenneth Coenegrachts; Hans Orlent; Leon ter Beek; Marc Haspeslagh; Shandra Bipat; Jaap Stoker; Hans Rigauts is a Medicine article available to read on EtoBox.
What is Improved focal liver lesion detection: Comparison of single-shot spin-echo echo-planar and superparamagnetic iron oxide (SPIO)-enhanced MRI about?
## Abstract ## Purpose To prospectively compare single‐shot spin‐echo echo‐planar imaging (SSSE‐EPI) using b = 0, 10, 150, and 400 seconds/mm^2^ with standard MRI techniques after intravenous super paramagnetic iron oxide (SPIO) in the detection and characterization of focal liver lesions with focus on small (<10 mm) focal liver lesions. ## Materials and Methods A total of 25 patients suspected for colorectal liver metastases were included. Number of detected lesions was evaluated. Image quality was compared between SSSE‐EPI sequence and post‐SPIO (fat‐suppressed T1‐weighted [T1w] gradient echo [GE], T2‐weighted [T2w] turbo spin echo [TSE] and T2\* GE) sequences using rank order statistic (RIDIT). Lesion characterization was performed for SSSE‐EPI and for all remaining sequences pre‐ and post‐SPIO. Reference standard comprised surgery, biopsy, and/or follow‐up. ## Results Reference standard demonstrated 25 hemangiomas and 70 metastases. Best lesion detection respectively best image quality (__P__ < 0.05) was achieved with SSSE‐EPI (b = 10 seconds/mm^2^) post‐SPIO T1w GE and T2w turbo spin echo. Lesion characterization using all sequences pre‐ and post‐SPIO performed best for lesion
Who reads Improved focal liver lesion detection: Comparison of single-shot spin-echo echo-planar and superparamagnetic iron oxide (SPIO)-enhanced MRI?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Kenneth Coenegrachts; Hans Orlent; Leon ter Beek; Marc Haspeslagh; Shandra Bipat; Jaap Stoker; Hans Rigauts
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)