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Can I read Determination of furazolidone in swine plasma, muscle, liver, kidney, fat and urine based on high-performance liquid chromatographic separation after solid-phase extraction on Extrelut 1 on EtoBox?
Determination of furazolidone in swine plasma, muscle, liver, kidney, fat and urine based on high-performance liquid chromatographic separation after solid-phase extraction on Extrelut 1 by Louis H.M. Vroomen; Marcel C.J. Berghmans; Teunis D.B. Van Der Struijs is a Chemistry article available to read on EtoBox.
What is Determination of furazolidone in swine plasma, muscle, liver, kidney, fat and urine based on high-performance liquid chromatographic separation after solid-phase extraction on Extrelut 1 about?
Furazolidone [N-(5-nitro-2-furfurylidene)-3-amino-2-oxazolidone], which is a nitrofuran, has been described as a potent antimicrobial agent for therapeutic and prophylactic purposes in pig, poultry and cattle '. Since furazolidone exhibits mutagenic and carcinogenic properties 2 ~ 4, the amount of furazolidone residue in edible products of food-producing animals treated with furdzolidone should be minimal. This requires sensitive analytical methods for the detection of furazolidone in liver, muscle, fat and kidney. In addition, methods for the detection of furazolidone in plasma or urine may be needed for screening purposes and pharmacokinetic studies. Many different methods have been described for the detection of furazolidone in tissues, milk, eggs, plasma and urine5-'6. Up till now, no suitable sensitive method has been described for the detection of furazolidone in plasma, muscle, liver, kidney, fat and urine. In this study, a relatively fast and sensitive high-performance liquid chromatographic (HPLC) method is described for the determination of furazolidone in plasma, muscle, liver, kidney, fat and urine of swine using a simple clean-up procedure based on solid-phase extracti
Who reads Determination of furazolidone in swine plasma, muscle, liver, kidney, fat and urine based on high-performance liquid chromatographic separation after solid-phase extraction on Extrelut 1?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Louis H.M. Vroomen; Marcel C.J. Berghmans; Teunis D.B. Van Der Struijs
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)
- Published
- 1986
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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