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Advances in Structure Pharmaceutics from Discovery to Evaluation and Design by Huipeng Xu; Li Wu; Yanling Xue; Ting Yang; Ting Xiong; Caifen Wang; Siyu He; Hongyu Sun; Zeying Cao; Jun Liu; Siwen Wang; Zhe Li; Abid Naeem; Xianzhen Yin; Jiwen Zhang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Advances in Structure Pharmaceutics from Discovery to Evaluation and Design about?
Drug delivery systems (DDSs) play an important role in delivering active pharmaceutical ingredients (APIs) to targeted sites with a predesigned release pattern. The chemical and biological properties of APIs and excipients have been extensively studied for their contribution to DDS quality and effectiveness; however, the structural characteristics of DDSs have not been adequately explored. Structure pharmaceutics involves the study of the structure of DDSs, especially the threedimensional (3D) structures, and its interaction with the physiological and pathological structure of organisms, possibly influencing their release kinetics and targeting abilities. A systematic overview of the structures of a variety of dosage forms, such as tablets, granules, pellets, microspheres, powders, and nanoparticles, is presented. Moreover, the influence of structures on the release and targeting capability of DDSs has also been discussed, especially the in vitro and in vivo release correlation and the structure-based organ-and tumor-targeting capabilities of particles with different structures. Additionally, an in-depth discussion is provided regarding the application of structural strategies in t
Who reads Advances in Structure Pharmaceutics from Discovery to Evaluation and Design?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Huipeng Xu; Li Wu; Yanling Xue; Ting Yang; Ting Xiong; Caifen Wang; Siyu He; Hongyu Sun; Zeying Cao; Jun Liu; Siwen Wang; Zhe Li; Abid Naeem; Xianzhen Yin; Jiwen Zhang
- Publisher
- American Chemical Society (ACS)
- Published
- 2023
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)