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Imaging the changes in renal T ~1~ induced by the inhalation of pure oxygen: A feasibility study by Richard A. Jones; Mario Ries; Chrit T.W. Moonen; Nicolas Grenier is a Medicine article available to read on EtoBox.

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## Abstract The effect of the inhalation of pure oxygen on the kidney was evaluated by measuring monoexponential __T__~1~ and __T__ relaxation times in nine volunteers using a multiple‐shot turbo spin echo and multiple echo gradient echo sequences, respectively. The __T__~1~ of the renal cortex decreased significantly when breathing pure oxygen as compared to normoxia (from 882 ± 59 to 829 ± 70 msec, __P__ < 0.05), while that of the renal medulla was unchanged. No significant changes were seen in the __T__ of either compartment. Dynamic imaging using an inversion recovery sequence with an optimized inversion time typically produced signal changes of 20% in the renal cortex. Studies to assess if oxygen‐induced changes in flow contributed to this effect showed that the flow contribution was not significant. Although longer inversion times (880 ms) produced optimal contrast, acceptable contrast was also obtained at shorter inversion times (450 msec) in the renal cortex, spleen, and lung, with the latter being of opposite polarity to the other two tissues, implying a shorter parenchymal __T__~1~ than previously reported in the literature. The results are consistent with oxygen acting a

Who reads Imaging the changes in renal T ~1~ induced by the inhalation of pure oxygen: A feasibility study?

Author

Richard A. Jones; Mario Ries; Chrit T.W. Moonen; Nicolas Grenier

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)

Published

2002

Language

EN

Field

Medicine (Health Sciences)