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Differential DNA methylation in Pacific oyster reproductive tissue in response to ocean acidification by Yaamini R. Venkataraman; Samuel J. White; Steven B. Roberts is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Differential DNA methylation in Pacific oyster reproductive tissue in response to ocean acidification about?

## Background: There is a need to investigate mechanisms of phenotypic plasticity in marine invertebrates as negative effects of climate change, like ocean acidification, are experienced by coastal ecosystems. environmentally-induced changes to the methylome may regulate gene expression, but methylome responses can be species- and tissue-specific. tissue-specificity has implications for gonad tissue, as gonad-specific methylation patterns may be inherited by offspring. we used the pacific oyster (crassostrea gigas) - a model for understanding ph impacts on bivalve molecular physiology due to its genomic resources and importance in global aquaculture- to assess how low ph could impact the gonad methylome. oysters were exposed to either low ph (7.31 ± 0.02) or ambient ph (7.82 ± 0.02) conditions for 7 weeks. whole genome bisulfite sequencing was used to identify methylated regions in female oyster gonad samples. c- > t single nucleotide polymorphisms were identified and removed to ensure accurate methylation characterization. ## Results: Analysis of gonad methylomes revealed a total of 1284 differentially methylated loci (dml) found primarily in genes, with several genes containing m

Who reads Differential DNA methylation in Pacific oyster reproductive tissue in response to ocean acidification?

Author

Yaamini R. Venkataraman; Samuel J. White; Steven B. Roberts

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)