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What is Efficacy of Lamotrigine in Bipolar Depression about?

This review article analyzes the efficacy of lamotrigine in treating bipolar depression through a meta-analysis of individual patient data from five randomized trials. The findings indicate that lamotrigine is superior to placebo in reducing depressive symptoms, particularly in patients with more severe depression, although the overall effect is modest. The study concludes that lamotrigine has a beneficial effect on depressive symptoms in bipolar disorder, with a number needed to treat (NNT) of 11 to 13 for

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gbwhmttdnj

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EN