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Can I read Toll-like Receptor Activation by Helminths or Helminth Products to Alleviate Inflammatory Bowel Disease on EtoBox?
Toll-like Receptor Activation by Helminths or Helminth Products to Alleviate Inflammatory Bowel Disease by ShuMin Sun; XueLin Wang; XiuPing Wu; Ying Zhao; Feng Wang; XiaoLei Liu; YanXia Song; ZhiLiang Wu; MingYuan Liu is a Medicine article available to read on EtoBox.
What is Toll-like Receptor Activation by Helminths or Helminth Products to Alleviate Inflammatory Bowel Disease about?
Helminth infection may modulate the expression of Toll like receptors (TLR) in dendritic cells (DCs) and modify the responsiveness of DCs to TLR ligands. This may regulate aberrant intestinal inflammation in humans with helminthes and may thus help alleviate inflammation associated with human inflammatory bowel disease (IBD). Epidemiological and experimental data provide further evidence that reducing helminth infections increases the incidence rate of such autoimmune diseases. Fine control of inflammation in the TLR pathway is highly desirable for effective host defense. Thus, the use of antagonists of TLR-signaling and agonists of their negative regulators from helminths or helminth products should be considered for the treatment of IBD.
Who reads Toll-like Receptor Activation by Helminths or Helminth Products to Alleviate Inflammatory Bowel Disease?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- ShuMin Sun; XueLin Wang; XiuPing Wu; Ying Zhao; Feng Wang; XiaoLei Liu; YanXia Song; ZhiLiang Wu; MingYuan Liu
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2008-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc.; Research Square (ISSN 1756-3305)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)