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The Impact of Clinical Maternal Chorioamnionitis on Neurological and Psychological Sequelae in Very-low-birth Weight Infants: a Case-control Study by Francesc Botet; Josep Figueras; Xavier Carbonell-Estrany; Eduardo Narbona is a Medicine article available to read on EtoBox.

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## Aims: To assess the relationship between clinically maternal chorioamnionitis and outcome in preterm very-low-birth weight (vlbw) infants. ## Methods: An observational case-control study was conducted in the neonatology departments of 12 acute care teaching hospitals in spain. between january 2004 and december 2006, all consecutive vlbw (≤1500 g) infants who were born to a mother with clinical chorioamnionitis were enrolled. the controls included infants who were born to mothers without chorioamnionitis, matched by gestational age, and immediately born after each index case. at a corrected age of 24 months, a neurological examination and a psychological assessment of the surviving children were performed. ## Results: Sixty-six of the newborn infants died; therefore, 262 infants from the original sample were available for the study. follow-up data were obtained at a corrected age of 24 months from a total of 209 children (106 cases and 103 controls, 80% of the original sample size). seventy children (33.5%) were diagnosed with some type of sequelae. the following conditions were all more prevalent in infants born to mothers with chorioamnionitis in comparison to controls: low dev

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Author

Francesc Botet; Josep Figueras; Xavier Carbonell-Estrany; Eduardo Narbona

Publisher

Walter de Gruyter GmbH

Published

2011

Language

EN

Field

Medicine (Health Sciences)