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Agitation is important for scaled-up fermentation procedures to ensure adequate mixing, prevent toxic buildup, maintain uniform pH and temperature, and transfer oxygen from bubbles to liquid. However, excessive agitation can cause hydromechanical stress and increased temperature. Growth medium must also be optimized to avoid inhibition from high concentrations of nutrients like glucose, ammonia, iron, magnesium, phosphorus, and zinc when attempting to generate high-density cultures. Oxygen delivery is impac

Author

Radhika Konakalla

Language

EN