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Can I read Copper and Melanin Play a Role in Myxococcus xanthus Predation on Sinorhizobium meliloti on EtoBox?
Copper and Melanin Play a Role in Myxococcus xanthus Predation on Sinorhizobium meliloti by Contreras-Moreno, Francisco Javier; Muñoz-Dorado, José; García-Tomsig, Natalia Isabel; Martínez-Navajas, Gonzalo; Pérez, Juana; Moraleda-Muñoz, Aurelio is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Copper and Melanin Play a Role in Myxococcus xanthus Predation on Sinorhizobium meliloti about?
__Myxococcus xanthus__ is a soil myxobacterium that exhibits a complex lifecycle with two multicellular stages: cooperative predation and development. During predation, myxobacterial cells produce a wide variety of secondary metabolites and hydrolytic enzymes to kill and consume the prey. It is known that eukaryotic predators, such as ameba and macrophages, introduce copper and other metals into the phagosomes to kill their prey by oxidative stress. However, the role of metals in bacterial predation has not yet been established. In this work, we have addressed the role of copper during predation of __M. xanthus__ on __Sinorhizobium meliloti__. The use of biosensors, variable pressure scanning electron microscopy, high-resolution scanning transmission electron microscopy, and energy dispersive X ray analysis has revealed that copper accumulates in the region where predator and prey collide. This accumulation of metal up-regulates the expression of several mechanisms involved in copper detoxification in the predator (the P~1~~B~-ATPase CopA, the multicopper oxidase CuoA and the tripartite pump Cus2), and the production by the prey of copper-inducible melanin, which is a polymer with
Who reads Copper and Melanin Play a Role in Myxococcus xanthus Predation on Sinorhizobium meliloti?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Contreras-Moreno, Francisco Javier; Muñoz-Dorado, José; García-Tomsig, Natalia Isabel; Martínez-Navajas, Gonzalo; Pérez, Juana; Moraleda-Muñoz, Aurelio
- Publisher
- Frontiers; Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2010-; Publons (ISSN 1664-302X)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)