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Perfusion for Hyperthermic Intraperitoneal Chemotherapy by Cardiopulmonary Bypass Machine by Mustafa Duman; Erdal Polat; Mehmet Can; Kaan Kırali; Ercan Ersoy is a book available to read on EtoBox.

What is Perfusion for Hyperthermic Intraperitoneal Chemotherapy by Cardiopulmonary Bypass Machine about?

Peritoneal carcinomatosis is malignancy of the peritoneum with a low incidence caused primary by peritoneum itself or secondary due to spread from the other organs, especially from ovarian, gastrointestinal systems including colorectal, appendical, and gastric malignancies. It is resistant to conventional chemotherapy and has a poor prognosis. Stages of the peritoneal metastatic cascade include dissociation from primary tumor, spreading to peritoneum, invasion of subperitoneal area, proliferation, and angiogenesis. To improve treatment outcomes, survival, and quality of life, various therapies have been developed and combination of the cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is the most popular approach due to its potentially curative and aggressive nature. Cancer should be isolated to the peritoneal cavity, a form of locoregional disease, to benefit from the effective CRS–HIPEC. The aim of CRS is to remove the peritoneum and organs if necessary, until no visible tumor remains. Elimination of the microscopic tumor foci in the peritoneal space is aimed by applying HIPEC using a warmed solution (41°C–43°C) after the surgical removal of macro

Author

Mustafa Duman; Erdal Polat; Mehmet Can; Kaan Kırali; Ercan Ersoy

Publisher

Elsevier Science & Technology

Published

2023

Language

EN

ISBN

9780323993029