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This research article analyzes data from 374 laboratories regarding the performance of different primary antibody clones used for Ki-67 staining in breast cancer over eight assessment runs from 2013 to 2017. The study found that the 30-9 and K2 clones had the highest mean scores for staining quality, while the MIB-1 clone was less effective. The findings emphasize the importance of both primary antibody selection and matching it with appropriate methodological factors to improve staining quality.

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ktybf29857

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EN