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Can I read GBA-associated PD: chances and obstacles for targeted treatment strategies on EtoBox?
GBA-associated PD: chances and obstacles for targeted treatment strategies by Günter Höglinger; Claudia Schulte; Wolfgang H. Jost; Alexander Storch; Dirk Woitalla; Rejko Krüger; Björn Falkenburger; Kathrin Brockmann is a Neuroscience article available to read on EtoBox.
What is GBA-associated PD: chances and obstacles for targeted treatment strategies about?
Abstract Given the clear role of GBA in the pathogenesis of Parkinson’s disease (PD) and its impact on phenotypical characteristics, this review provides an overview of the current knowledge of GBA-associated PD with a special focus on clinical trajectories and the underlying pathological mechanisms. Importantly, differences and characteristics based on mutation severity are recognized, and current as well as potential future treatment options are discussed. These findings will inform future strategies for patient stratification and cohort enrichment as well as suitable outcome measures when designing clinical trials.
Who reads GBA-associated PD: chances and obstacles for targeted treatment strategies?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Günter Höglinger; Claudia Schulte; Wolfgang H. Jost; Alexander Storch; Dirk Woitalla; Rejko Krüger; Björn Falkenburger; Kathrin Brockmann
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Neuroscience (Life Sciences)