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Effect of Scanner in Longitudinal Diffusion Tensor Imaging Studies by Hidemasa Takao; Naoto Hayashi; Hiroyuki Kabasawa; Kuni Ohtomo is a Neuroscience article available to read on EtoBox.

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## Abstract The purpose of this study was to evaluate the effects of longitudinal drift in scanner hardware, inter‐scanner variability (bias), and scanner upgrade on longitudinal changes in global and regional diffusion properties using longitudinal data obtained on two scanners of the exact same model at one institution. A total of 224 normal subjects were scanned twice, at an interval of about 1 year, using two 3.0‐T scanners of the exact same model. Both scanners were simultaneously upgraded during the study period. The subjects were divided into four groups according to the combination of scanners used. With use of tract‐based spatial statistics, we evaluated the effects of scanner drift and inter‐scanner variability (bias) on global and regional fractional anisotropy (FA), axial diffusivity (AD), and radial diffusivity (RD) changes of the white matter. Even with scanners of the exact same model, inter‐scanner variability (bias) significantly affected longitudinal results. FA, AD, and RD of the white matter were relatively stable within the same scanner. We also investigated the effect of scanner upgrade on longitudinal FA, AD, and RD changes. The scanner upgrade included only

Who reads Effect of Scanner in Longitudinal Diffusion Tensor Imaging Studies?

Author

Hidemasa Takao; Naoto Hayashi; Hiroyuki Kabasawa; Kuni Ohtomo

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1065-9471)

Published

2011

Language

EN

Field

Neuroscience (Life Sciences)