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Can I read Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe on EtoBox?
Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe by James R. Kinghorn; Rudolf Fluri is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe about?
Purines such as hypoxanthine, xanthine, uric acid, allantoin and allantoic acid serve as sole nitrogen sources for the yeast Schizosaccharomyces pombe. A number of classes of mutants unable to use purines have been isolated and genetically analysed. Mutants in the urol gene lack uricase, alll lack allantoinase, alal lack allantoicase whilst in urel, ure2, ure3 and ure4 genes lack urease activity. Mutants in four hyp genes are unable to convert hypoxanthine to uric acid whilst mutation in xan 1 results in impaired growth with xanthine. hyp5 strains are unable to convert both hypoxanthine and xanthine to uric acid. The mutations are recessive and none of the loci are linked to each other. The possible catalytic steps involved are discussed.
Who reads Genetic studies of purine breakdown in the fission yeast Schizosaccharomyces pombe?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- James R. Kinghorn; Rudolf Fluri
- Publisher
- Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC (ISSN 0172-8083)
- Published
- 1984
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)