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The study investigates the effects of low concentrations of dimethyl sulfoxide (DMSO) on the intrinsic excitability of cortical and hippocampal pyramidal neurons. It finds that a 0.05% DMSO treatment alters neuronal properties, decreasing input resistance and action potential output in CA1 pyramidal cells, while increasing action potential width in perirhinal cortex cells. These findings suggest that even low concentrations of DMSO can have significant neurophysiological effects, challenging the notion of i

Author
frank.w.dong
Language
EN