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Can I read Harms of Exercise Training in Patients with Cancer Undergoing Systemic Treatment: a Systematic Review and Meta-analysis of Published and Unpublished Controlled Trials on EtoBox?
Harms of Exercise Training in Patients with Cancer Undergoing Systemic Treatment: a Systematic Review and Meta-analysis of Published and Unpublished Controlled Trials by Simon N. Thomsen; Ian M. Lahart; Laura M. Thomsen; Martin K. Fridh; Anders Larsen; Morten Mau-Sørensen; Kate A. Bolam; Ciaran M. Fairman; Jesper F. Christensen; Casper Simonsen is a Medicine article available to read on EtoBox.
What is Harms of Exercise Training in Patients with Cancer Undergoing Systemic Treatment: a Systematic Review and Meta-analysis of Published and Unpublished Controlled Trials about?
Background Exercise is recommended for people with cancer. The aim of this study was to evaluate the harms of exercise in patients with cancer undergoing systemic treatment. Methods This systematic review and meta-analysis included published and unpublished controlled trials comparing exercise interventions versus controls in adults with cancer scheduled to undergo systemic treatment. The primary outcomes were adverse events, health-care utilization, and treatment tolerability and response. Eleven electronic databases and trial registries were systematically searched with no date or language restrictions. The latest searches were performed on April 26, 2022. The risk of bias was judged using RoB2 and ROBINS-I, and the certainty of evidence for primary outcomes was assessed using GRADE. Data were statistically synthesised using pre-specified random-effect meta-analyses. The protocol for this study was registered in the PROESPERO database (ID: CRD42021266882). Findings 129 controlled trials including 12,044 participants were eligible. Primary meta-analyses revealed evidence of a higher risk of some harms, including serious adverse events (risk ratio [95% CI]: 1.87 [1.47–2.39], I2 = 0
Who reads Harms of Exercise Training in Patients with Cancer Undergoing Systemic Treatment: a Systematic Review and Meta-analysis of Published and Unpublished Controlled Trials?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Simon N. Thomsen; Ian M. Lahart; Laura M. Thomsen; Martin K. Fridh; Anders Larsen; Morten Mau-Sørensen; Kate A. Bolam; Ciaran M. Fairman; Jesper F. Christensen; Casper Simonsen
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)