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2 Artículo Bioetica by juliogamer854 is a document available to read on EtoBox.
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The document discusses the CRISPR/Cas systems in bacteria and archaea, focusing on the Type II system which utilizes a dual-RNA mechanism involving crRNA and tracrRNA to guide the Cas9 protein for site-specific DNA cleavage. The study reveals that the Cas9 endonuclease requires a base-paired structure between tracrRNA and crRNA to effectively cleave target DNA, highlighting the potential for RNA-programmable genome editing. The findings emphasize the importance of specific sequence motifs, such as the proto
- Author
- juliogamer854
- Language
- EN