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Quantification of airway dimensions using a high‐resolution CT scanner: A phantom study by Yixiao Zhao; Andrew M. Hernandez; John M. Boone; Sabee Molloi is a Medicine article available to read on EtoBox.
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## Abstract ## Purpose Small airways with inner diameters less than 2 mm are sites of major airflow limitations in patients with chronic obstructive pulmonary disease (COPD) and asthma. The purpose of this study is to investigate the limitations for accurate assessment of small airway dimensions using both high‐resolution CT (HRCT) and conventional normal‐resolution CT at low dose levels. ## Methods To model the normal human airways from the 3rd to 20th generations, a cylindrical polyurethane phantom with 14 airway tubes of inner diameters (ID) ranging from 0.3 to 3.4 mm and wall thicknesses (WT) ranging from 0.15 to 1.6 mm was placed within an Anthropomorphic QRM‐Thorax phantom. The Aquilion Precision (Canon Medical Systems Corporation) HRCT scanner was used to acquire images at 80, 100, and 120 kV using high resolution mode (HR, 0.25 mm × 160 detector configuration) and normal‐resolution (NR) mode (0.5 mm × 80 detector configuration). The HR data were reconstructed using a 1024 × 1024 matrix (0.22 × 0.22 × 0.25 mm voxel size) and the NR data were reconstructed using a 512 × 512 matrix (0.43 × 0.43 × 0.50 mm). Two reconstruction algorithms (filtered back projection; FBP and an ada
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- Author
- Yixiao Zhao; Andrew M. Hernandez; John M. Boone; Sabee Molloi
- Publisher
- Wiley
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)
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