About this Medicine article

Study of selected birth defects among American Indian/Alaska Native population: A multi‐state population‐based retrospective study, 1999–2007 by Lisa K. Marengo; Timothy J. Flood; Mary K. Ethen; Russell S. Kirby; Sarah Fisher; Glenn Copeland; Robert E. Meyer; Julie Dunn; Mark A. Canfield; Tom Anderson; Del Yazzie; Cara T. Mai; for the National Birth Defects Prevention Network is a Medicine article available to read on EtoBox.

## Background: Higher prevalence of selected birth defects has been reported among american indian/alaska native (ai/an) newborns. we examine whether known risk factors for birth defects explain the higher prevalence observed for selected birth defects among this population. ## Methods: Data from 12 population-based birth defects surveillance systems, covering a birth population of 11 million from 1999 to 2007, were used to examine prevalence of birth defects that have previously been reported to have elevated prevalence among ai/ans. prevalence ratios (prs) were calculated for non-hispanic ai/ans and any ai/ans (regardless of hispanic ethnicity), adjusting for maternal age, education, diabetes, and smoking, as well as type of case-finding ascertainment surveillance system. ## Results: After adjustment, the birth prevalence of two of seven birth defects remained significantly elevated among ai/ans compared to non-hispanic whites (nhws): anotia/microtia was almost threefold higher, and cleft lip +/- cleft palate was almost 70% higher compared to nhws. excluding ai/an subjects who were also hispanic had only a negligible impact on adjusted prs. ## Conclusions: Additional covariates a

Author

Lisa K. Marengo; Timothy J. Flood; Mary K. Ethen; Russell S. Kirby; Sarah Fisher; Glenn Copeland; Robert E. Meyer; Julie Dunn; Mark A. Canfield; Tom Anderson; Del Yazzie; Cara T. Mai; for the National Birth Defects Prevention Network

Publisher

Wiley

Published

2018

Language

EN

Field

Medicine (Health Sciences)