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Deconstructing organs: From decellularized organs, and stem cells niche to constructed organoids and engineering new organs by Rodrigo R. Resende is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Deconstructing organs: From decellularized organs, and stem cells niche to constructed organoids and engineering new organs about?

Organs-on-a-chip biotechnologies for neurogenesis stem cells niche organoids organs engineering microfluidics technologies bioprinting Modern biological and biomedical research is driven by model systems. These model systems attempt to mimic bodily functions and processes at the molecular, cellular, tissue, organ, and whole organism levels. The body can be viewed as a collection of a large number and wide variety of highly organized cellular and non-cellular materials (e. g., cell, tissue, and organ), as well as the entire interactome, which includes internal (e.g., cell-cell, cell-matrix) or external (e.g., cellenvironment) interactions. Since all living creatures are hierarchical, multi-level recapitulation of the body might be accomplished utilizing model systems comprised of many cell types and their interactions. Indeed, advances in 3D cell biology and engineering have resulted in the creation of a new generation of cell culture formats that can better mimic the in vivo milieu, allowing us to study cells and their interactions in a more biomimetic context. Modern biomedical research has various technical tools at its disposal that facilitate the production of increasingly comp

Who reads Deconstructing organs: From decellularized organs, and stem cells niche to constructed organoids and engineering new organs?

Author

Rodrigo R. Resende

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)