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What is Antibiotic Resistance Gene Duplication about?

This study investigates the role of horizontal gene transfer (HGT) and gene duplication in the evolution of antibiotic resistance genes (ARGs) in bacteria. Through modeling and experimental evolution, it is shown that antibiotic selection can drive the duplication of ARGs via mobile genetic elements, leading to an enrichment of these duplicated genes in environments with antibiotic use, particularly in clinical isolates. The findings suggest that duplicated ARGs are often associated with positive selection

Author

boramaks

Language

EN