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Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach by Aaron R. Kaufman; Elmer Y. Tu is a Medicine article available to read on EtoBox.
What is Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach about?
## A C T Acanthamoeba keratitis (AK) is a severe cause of infectious keratitis and represents a significant clinical challenge. Recent literature regarding AK epidemiology, diagnosis, treatment modalities, and prognosis is reviewed and synthesized to propose an algorithmic protocol for AK management. Globally, AK outbreaks in developed countries are ongoing, and AK rates have increased. Moreover, current outbreaks may carry a worse prognosis than prior outbreaks. Despite identification of contact lens solutions implicated in AK outbreaks and the consequent market recall of these products, outbreaks persist. Acanthamoeba keratitis afflicts not only refractive soft contact lens users but also cosmetic contact lens users and gas permeable (especially orthokeratology) lens users. Innovations in in vivo confocal microscopy and PCR assays have increased the role for these adjuvant tests alongside corneal smear and culture in a multimodal diagnostic approach to suspected AK. Biguanides (such as chlorhexidine and polyhexamethylene biguanide) and diamidines (propamidine isethionate and hexamidine) remain cornerstones of AK management, and evidence for other treatment modalities continues to
Who reads Advances in the management of Acanthamoeba keratitis: A review of the literature and synthesized algorithmic approach?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Aaron R. Kaufman; Elmer Y. Tu
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)