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Transfer of Antibiotic Resistance in Staphylococcus aureus by Jakob Haaber; José R. Penadés; Hanne Ingmer is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Transfer of Antibiotic Resistance in Staphylococcus aureus about?

Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers. Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance genes from other S. aureus strains or even from other genera. Transfer is mediated by a diverse complement of mobile genetic elements and occurs primarily by conjugation or bacteriophage transduction, with the latter traditionally being perceived as the primary route. Recent work on conjugation and transduction suggests that transfer by these mechanisms may be more extensive than previously thought, in terms of the range of plasmids that can be transferred by conjugation and the efficiency with which transduction occurs. Here, we review the main routes of antibiotic resistance gene transfer in S. aureus in the context of its biology as a human commensal and a life-threatening pathogen.

Who reads Transfer of Antibiotic Resistance in Staphylococcus aureus?

Author

Jakob Haaber; José R. Penadés; Hanne Ingmer

Publisher

Elsevier BV

Published

2017

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)