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Can I read Imaging Features of Immune Checkpoint Inhibitor-related Nephritis with Clinical Correlation: a Retrospective Series of Biopsy-proven Cases on EtoBox?
Imaging Features of Immune Checkpoint Inhibitor-related Nephritis with Clinical Correlation: a Retrospective Series of Biopsy-proven Cases by Muhammad O. Awiwi; Ala Abudayyeh; Noha Abdel-Wahab; Adi Diab; Migena Gjoni; Guofan Xu; Raghu Vikram; Khaled Elsayes is a Medicine article available to read on EtoBox.
What is Imaging Features of Immune Checkpoint Inhibitor-related Nephritis with Clinical Correlation: a Retrospective Series of Biopsy-proven Cases about?
## Objectives: Imaging appearances of immune checkpoint inhibitor-related nephritis have not yet been described. the primary objective of this study is to describe the appearances of immunotherapy-related nephritis on computerized tomography (ct) and positron emission tomography (pet). the secondary objectives are to investigate the association of radiologic features with clinical outcomes. ## Methods: Ct and pet-ct scans before the initiation of immunotherapy (baseline), at nephritis, and after resolution of pathology-proven nephritis cases were reviewed. total kidney volume, renal parenchymal suvmax, renal pelvis suvmax, and blood pool suvmean were obtained. ## Results: Thirty-four patients were included. the total kidney volume was significantly higher at nephritis compared to baseline (464.7 ± 96.8 ml vs. 371.7 ± 187.7 ml; p 30% increase in total kidney volume, which was associated with significantly higher renal toxicity grade (p = 0.007), higher peak creatinine level (p = 0.004), and more aggressive medical treatment (p = 0.011). new/increasing perinephric fat stranding was noted in 10 patients (29.4%) at nephritis. among 8 patients with contrast-enhanced ct at nephritis, o
Who reads Imaging Features of Immune Checkpoint Inhibitor-related Nephritis with Clinical Correlation: a Retrospective Series of Biopsy-proven Cases?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Muhammad O. Awiwi; Ala Abudayyeh; Noha Abdel-Wahab; Adi Diab; Migena Gjoni; Guofan Xu; Raghu Vikram; Khaled Elsayes
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)