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What is Plasma Data Analysis Post-Bolus Input about?
PKSolver was used to perform non-compartmental and compartmental analyses of plasma concentration data after a 250 mg intravenous bolus dose. The non-compartmental analysis estimated an elimination half-life of 4.07 hours, AUC of 49.75 μg/ml*h, and clearance of 4.80 L/h. The compartmental analysis fit the data to a one-compartment model with an elimination rate constant of 1/h and estimated volume of distribution of 19.7 L.
- Author
- hanutamib
- Language
- EN