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Familial adenomatous polyposis (FAP) is a genetic disorder characterized by the development of numerous colorectal adenomatous polyps, with a high risk of colorectal cancer if untreated. The condition is caused by mutations in the APC gene and follows an autosomal dominant inheritance pattern, with various clinical manifestations including extracolonic tumors and other syndromes. Diagnosis typically involves identifying a significant number of adenomas and may require genetic testing to confirm the presence

Author

Sushil Gyawali

Language

EN