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The Ancestral and Industrialized Gut Microbiota and Implications for Human Health by Erica D. Sonnenburg; Justin L. Sonnenburg is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is The Ancestral and Industrialized Gut Microbiota and Implications for Human Health about?

Human-associated microbial communities have adapted to environmental pressures. Doses of antibiotics select for a community with increased antibiotic resistance, inflammation is accompanied by expansion of community members equipped to flourish in the presence of immune effectors and Western diets shift the microbiota away from fibre degraders in favour of species that thrive on mucus. Recent data suggest that the microbiota of industrialized societies differs substantially from the recent ancestral microbiota of humans. Rapid modernization, including medical practices and dietary changes, is causing progressive deterioration of the microbiota, and we hypothesize that this may contribute to various diseases prevalent in industrialized societies. In this Opinion article, we explore whether individuals in the industrialized world may be harbouring a microbial community that, while compatible with our environment, is now incompatible with our human biology.

Who reads The Ancestral and Industrialized Gut Microbiota and Implications for Human Health?

Author

Erica D. Sonnenburg; Justin L. Sonnenburg

Publisher

Springer Science and Business Media LLC

Published

2019

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)