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The effect of sage (Salvizan gel) compared to triamcinolone acetonide on the treatment of recurrent aphthous stomatitis: a double-blinded randomized clinical trial by Fatemeh Abbasi; Zeinab Rasoulzadeh; Amirmohammad Yavari is a Dentistry article available to read on EtoBox.

What is The effect of sage (Salvizan gel) compared to triamcinolone acetonide on the treatment of recurrent aphthous stomatitis: a double-blinded randomized clinical trial about?

## Background Recurrent Aphthous Stomatitis (RAS) is one of the most common lesions of the oral mucosa. Herbal medicine can be used for the treatment of this disease. The present study aimed to compare the effects of topical application of Sage (Salvizan) and triamcinolone acetonide gels on RAS. ## Methods This double-blind clinical study recruited sixty patients with minor aphthous ulcers. Half of the patients were treated with Salvizan gel, and the other half were treated with oral triamcinolone acetonide gel. The effect of Salvizan topical gel was evaluated and compared with that of oral triamcinolone acetonide gel. Factors such as Pain recovery time, wound healing time, and pain level was evaluated. Data were analyzed by SPSS version 22 using independent t-test, paired t-test, repeated measures ANOVA, and survival analysis, including Kaplan-Meier and Cox regression. ## Results The mean duration of pain recovery was 1.5 days for Salvizan and 2.5 days for triamcinolone acetonide (__p__ < 0.001). Moreover, the duration of wound healing was 3.3 days for Salvizan and 6 days for triamcinolone acetonide (__p__ < 0.001). Patients’ satisfaction from factors such as taste and smell had n

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Author

Fatemeh Abbasi; Zeinab Rasoulzadeh; Amirmohammad Yavari

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Dentistry (Health Sciences)