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DHODH Inhibitors Against SARS-CoV-2 by Daniel Benitez is a document available to read on EtoBox.
What is DHODH Inhibitors Against SARS-CoV-2 about?
This editorial discusses the potential of dihydroorotate dehydrogenase (DHODH) inhibitors as a treatment for SARS-CoV-2 infection, highlighting their role in disrupting the de novo pyrimidine synthesis pathway essential for viral replication. The authors emphasize that DHODH inhibitors, such as leflunomide and brequinar, have shown antiviral activity against various viruses and may enhance innate immune responses. Ongoing clinical trials are exploring the efficacy of these inhibitors in treating COVID-19, w
- Author
- Daniel Benitez
- Language
- EN