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Can I read Human liver autofluorescence: An intrinsic tissue parameter discriminating normal and diseased conditions on EtoBox?
Human liver autofluorescence: An intrinsic tissue parameter discriminating normal and diseased conditions by Anna C. Croce; Uliana De Simone; Isabel Freitas; Eleonora Boncompagni; Daniele Neri; Umberto Cillo; Giovanni Bottiroli is a Medicine article available to read on EtoBox.
What is Human liver autofluorescence: An intrinsic tissue parameter discriminating normal and diseased conditions about?
## Abstract ## Background and Objective Autofluorescence (AF) emission is an intrinsic parameter that can provide real‐time information on morpho‐functional properties of biological tissue, being strictly related with their biochemical composition and structural organization. The diagnostic potentials of AF‐based techniques have been investigated on normal, fibrotic, and steatotic liver tissues, in reference to histological features as evidenced by specific histochemical stainings. ## Materials and Methods AF emission under excitation at 366 nm has been examined on cryostatic tissue sections obtained from biopsies collected during surgical operation, by means of fluorescence imaging and microspectrofluorometric techniques. ## Results NAD(P)H, collagen, and vitamin A were found to be the endogenous fluorophores characterizing normal, fibrotic, and steatotic liver tissue AF, respectively. The differences of their photo‐physical properties, in terms of emission amplitude, spectral shape, and response to irradiation, give rise to modifications of overall AF signal collected from tissues that allow the liver conditions to be distinguished. ## Conclusion The study provides a valid premis
Who reads Human liver autofluorescence: An intrinsic tissue parameter discriminating normal and diseased conditions?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Anna C. Croce; Uliana De Simone; Isabel Freitas; Eleonora Boncompagni; Daniele Neri; Umberto Cillo; Giovanni Bottiroli
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0196-8092)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)