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Can I read Diabetes insipidus after endoscopic transsphenoidal surgery: multicenter experience and development of the SALT score on EtoBox?
Diabetes insipidus after endoscopic transsphenoidal surgery: multicenter experience and development of the SALT score by Mendel Castle-Kirszbaum; Peter Fuller; Yi Yuen Wang; James King; Tony Goldschlager is a Medicine article available to read on EtoBox.
What is Diabetes insipidus after endoscopic transsphenoidal surgery: multicenter experience and development of the SALT score about?
## Objective: To identify risk factors for the development of postoperative diabetes insipidus (di) in a modern cohort of endoscopic endonasal transsphenoidal surgery. ## Methods: Analysis of prospectively collected data of 449 consecutive patients operated on for anterior skull base pathology. di was defined as a polyuria (> 250 ml/h for ≥ 2 consecutive hours) polydipsia syndrome associated with hypotonic urine with or without hypernatraemia. multivariate logistic regression was used to identify predictors of postoperative di. a simple scoring system was then created. ## Results: Postoperative di occurred in 46 (10.2%) patients. the development of di did not affect quality of life. predictors of di on multivariate analysis included suprasellar extension (or 2.2; p = 0.04), age < 50 years (or 2.8; p = 0.003), craniopharyngioma histology (or 6.7; p = 0.002), and kelly grade 3 intraoperative csf leak (or 2.1; p = 0.04). the salt score was created based on these characteristics, with one point awarded for each feature present, and predicted di with fair to good predictive value in our cohort (auroc 0.735 (95%ci 0.65-0.82)). the rates of postoperative di were 4.0%, 6.5%, 15.0%. 36.8% a
Who reads Diabetes insipidus after endoscopic transsphenoidal surgery: multicenter experience and development of the SALT score?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mendel Castle-Kirszbaum; Peter Fuller; Yi Yuen Wang; James King; Tony Goldschlager
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)