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Effect of Age on Biomaterial-mediated in situ Bone Tissue Regeneration by Liu, Mengqian; Nakasaki, Manando; Vernon Shih, Yu-Ru; Varghese, Shyni is a Engineering article available to read on EtoBox.

What is Effect of Age on Biomaterial-mediated in situ Bone Tissue Regeneration about?

## Statement of significance: Tissue engineering strategies that promote tissue repair through recruitment of endogenous cells will have a significant impact in regenerative medicine. previous studies from our group have shown that biomineralized materials containing calcium phosphate minerals can contribute to neo-bone tissue through recruitment and activation of endogenous cells. in this study, we investigated the effect of age of the recipient on biomaterial-mediated bone tissue repair. our results show that the age of the recipient mouse had a significant impact on the quality and quantity of the engineered neo-bone tissues, in which delayed/compromised bone tissue formation was observed in older mice. these findings are in agreement with the clinical observations that age of patients is a key factor in bone repair.

Who reads Effect of Age on Biomaterial-mediated in situ Bone Tissue Regeneration?

Author

Liu, Mengqian; Nakasaki, Manando; Vernon Shih, Yu-Ru; Varghese, Shyni

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1742-7061)

Published

2018

Language

EN

Field

Engineering (Physical Sciences)