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Can I read cAMP-dependent protein kinase from Dictyostelium discoideum on EtoBox?
cAMP-dependent protein kinase from Dictyostelium discoideum by Michel Veron; Rupert Mutzel; Marie-Lise Lacombe; Marie-Noëlle Simon; Valérie Wallet is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is cAMP-dependent protein kinase from Dictyostelium discoideum about?
The CAMP-dependent protein kinase (cAK) from Diciyosteliurn discoideurn is an enzyme composed of one catalytic and one regulatory subunit. Upon binding of CAMP, the holoenzyme dissociates to liberate free active catalytic subunits. The cAK is developmentally regulated, ranging from very little activity in vegetative cells to maximal expression in postaggregative cells. Although there is no immunological cross-reaction between the subunits of cAKs from Diciyosteliurn and from other organisms, they share several hiochemical properties. A complete cDNA for the regulatory subunit has been cloned and sequenced. Only one copy of the gene for the regulatory subunit is present per haploid genome. On the basis of the comparison of the structure of the cAK from Dicryosteliurn with its counterparts in yeast and higher eukaryotes, we propose a model for the evolution of cyclic-nucleotide-binding proteins.
Who reads cAMP-dependent protein kinase from Dictyostelium discoideum?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Michel Veron; Rupert Mutzel; Marie-Lise Lacombe; Marie-Noëlle Simon; Valérie Wallet
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0192-253X)
- Published
- 1987
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)