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Chronic Urticaria and Thyroid Autoimmunity Markers by Anzelika Chomiciene; Laimute Jurgauskiene; Audra Blaziene is a Medicine article available to read on EtoBox.

What is Chronic Urticaria and Thyroid Autoimmunity Markers about?

The association of chronic urticaria and autoimmune thyroid disease has been well recognized. Some authors observed relationship between thyroid autoimmunity and chronic autoimmune urticaria. Objective. The primary objective was to evaluate thyroid autoimmunity and thyroid function in chronic urticaria. Secondary objective was to correlate results of antibodies to thyroid peroxidase and markers of autoimmune urticaria (autologous serum skin test and CD63 expression). Materials and methods. 128 patients with chronic urticaria were evaluated for antibodies to thyroid peroxidase, autologous serum skin test and donor basophil CD63 expression induced by patients sera. Thyroid-stimulating hormone was performed in all patients with elevated antibodies to thyroid peroxidase and 48 patients with normal level of antibodies. Results. Antibodies to thyroid peroxidase were elevated in 25.0% patients. Thyroid function was abnormal in 28.1% patients with elevated antibodies to thyroid peroxidase and 8.3% patients with normal antibodies level. We did not find the relationship between thyroid antibodies and markers of autoimmune urticaria (autologous serum skin test and CD63 expression). Conclusion

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Author

Anzelika Chomiciene; Laimute Jurgauskiene; Audra Blaziene

Publisher

Walter de Gruyter GmbH

Published

2012

Language

EN

Field

Medicine (Health Sciences)