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What is Targeted Salinomycin Nanoparticles for Osteosarcoma about?

This manuscript presents the development of dual-ligand lipid-polymer nanoparticles that deliver salinomycin to both osteosarcoma cells and cancer stem cells (CSCs) using EGFR and CD133 aptamers. The study demonstrates that these nanoparticles (CESP) show superior cytotoxicity and efficacy in inhibiting tumor growth compared to single-targeting approaches. The findings suggest that targeting both CSCs and cancer cells could enhance therapeutic outcomes in osteosarcoma treatment.

Author

IqF Say

Language

EN