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Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review by Ryan M. Kahn; Sushmita Gordhandas; Kendra Godwin; Rebecca L. Stone; Michael J. Worley; Karen H. Lu; Kara C. Long Roche is a Medicine article available to read on EtoBox.

What is Salpingectomy for the Primary Prevention of Ovarian Cancer: A Systematic Review about?

## Importance Most ovarian cancers originate in the fimbriated end of the fallopian tube. This has led to the hypothesis that surgical resection of the fallopian tubes at the time of gynecologic and nongynecologic surgical procedures—referred to as an opportunistic salpingectomy—may prevent the development of epithelial ovarian cancer for women at an average risk of developing the disease. ## Objective To compile a comprehensive, state-of-the-science review examining the current landscape of performing bilateral salpingectomy for ovarian cancer prevention. ## Evidence Review A systematic review of the literature was performed on March 4, 2022, to identify studies examining salpingectomy for ovarian cancer prevention. This review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) 2020 statement. Four databases were selected: PubMed via the National Library of Medicine’s PubMed.gov, Embase via Elsevier’s Embase.com, Cochrane Central Register of Controlled Trials (CENTRAL) via Wiley’s Cochrane Library, and Northern Light Life Sciences Conference Abstracts via Ovid. A total of 20 gray literature sources, including 1 database, 2 re

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Author

Ryan M. Kahn; Sushmita Gordhandas; Kendra Godwin; Rebecca L. Stone; Michael J. Worley; Karen H. Lu; Kara C. Long Roche

Publisher

American Medical Association (AMA)

Published

2023

Field

Medicine (Health Sciences)