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This study investigates the anticonvulsant effects of the leaf methanol extract of Tulbaghia violacea, traditionally used in South Africa for epilepsy treatment, through various convulsion models in mice. The extract demonstrated significant anticonvulsant activity, likely involving GABAergic, glutamatergic, and glycinergic mechanisms, and was found to contain several phytochemicals including alkaloids and flavonoids. The LD50 of the extract was determined to be over 4000 mg/kg, indicating a relatively low

Author

Sabrina Jones

Language

EN