Opening book details…
Can I read Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: Improvement of potency in vitro and in vivo on EtoBox?
Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: Improvement of potency in vitro and in vivo by Hiroki Shimizu; Isao Yasumatsu; Tomoaki Hamada; Yoshiyuki Yoneda; Tomonori Yamasaki; Shinji Tanaka; Tadashi Toki; Mika Yokoyama; Kaoru Morishita; Shin Iimura is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: Improvement of potency in vitro and in vivo about?
1 (n=1) IKKβ: IC 50 = 0.055 μM TNFα: IC 50 = 0.69 μM (THP-1 cell) 2 (n=2) IKKβ: IC 50 = 0.047 μM TNFα: IC 50 = 1.5 μM ( ) n 3 (R 1 = H) IKKβ IC 50 = 0.20 μM TNFα: IC 50 = 0.69 μM 4 (R 1 = Me) IKKβ IC 50 = 0.33 μM TNFα: IC 50 = 2.4 μM
Who reads Discovery of imidazo[1,2-b]pyridazines as IKKβ inhibitors. Part 2: Improvement of potency in vitro and in vivo?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Hiroki Shimizu; Isao Yasumatsu; Tomoaki Hamada; Yoshiyuki Yoneda; Tomonori Yamasaki; Shinji Tanaka; Tadashi Toki; Mika Yokoyama; Kaoru Morishita; Shin Iimura
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2011
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)