Opening book details…
Can I read Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: Results from the Norfolk arthritis register on EtoBox?
Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: Results from the Norfolk arthritis register by Elizabeth M. Camacho; Suzanne M. M. Verstappen; Mark Lunt; Diane K. Bunn; Deborah P. M. Symmons is a Medicine article available to read on EtoBox.
What is Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: Results from the Norfolk arthritis register about?
## Abstract ## Objective It has been found that women with rheumatoid arthritis (RA) have a poorer prognosis than men. However, the impact of age at symptom onset is unclear. We investigated the relationship between these factors and functional disability in patients with recent‐onset inflammatory polyarthritis (IP). ## Methods A total of 3,666 patients (66% women) were registered with the Norfolk Arthritis Register between 1990 and 2008. Functional disability was assessed using the Health Assessment Questionnaire (HAQ), adjusted for age at HAQ completion. Linear random‐effects models were used to examine HAQ score over time, by sex and age at symptom onset (early = age <55 years, late = age 55–74 years, very late = age ≥75 years). ## Results Women had higher HAQ scores over time than men (mean difference 0.29; 95% confidence interval [95% CI] 0.25, 0.34). Men with late‐onset IP had lower baseline HAQ scores than men with early onset (mean difference −0.14; 95% CI −0.29, −0.001). Women had comparable baseline HAQ scores at all ages of onset. Both sexes showed the greatest rate of disability progression in patients with very late onset. Those with early onset had a steady level of d
Who reads Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: Results from the Norfolk arthritis register?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Elizabeth M. Camacho; Suzanne M. M. Verstappen; Mark Lunt; Diane K. Bunn; Deborah P. M. Symmons
- Publisher
- Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 2151-464X)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)