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Mobile genetic elements associated with carbapenemase genes in South American Enterobacterales by Reyes, Jorge Aníbal; Melano, Roberto; Cárdenas, PaÃol Andrés; Trueba, Gabriel is a Medicine article available to read on EtoBox.

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## Introduction Carbapenem resistance in members of order Enterobacterales is a growing public health problem causing high mortality in developing and industrialized countries. Its emergence and rapid propagation worldwide was due to both intercontinental spread of pandemic strains and horizontal dissemination via mobile genetic elements (MGE) such as plasmids and transposons. ## Objective To describe MGE carrying carbapenem resistance genes in Enterobacterales which have been reported in South America. ## Search strategy and selection criteria A search of the literature in English or Spanish published until 2019 in PubMed, Google Scholar, LILACS and SciELO databases was performed for studies of MGE in Enterobacterales reported in South American countries. ## Results Seven South American countries reported MGE related to carbapenemases. Carbapenemase-producing __Klebsiella pneumoniae__ belonging to clonal complex 258 were the most prevalent pathogens reported; others carbapenemase-producing Enterobacterales such as __Escherichia coli__, __Serratia marcescens__, and __Providencia rettgeri__ also have been reported. The MGE implicated in the spread of the most prevalent carbapenemase

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Author

Reyes, Jorge Aníbal; Melano, Roberto; Cárdenas, PaÃol Andrés; Trueba, Gabriel

Publisher

SciELO; Elsevier ; Elsevier Editora Ltda; Elsevier BV; FapUNIFESP (SciELO); Salvador BA: Sociedade Brasileira de Doenças Infecciosas; Barcelona: Elsevier España (ISSN 1413-8670)

Published

2020

Language

EN

Field

Medicine (Health Sciences)