Can I read Smoking Cessation Is Associated with Lower Disease Activity and Predicts Cardiovascular Risk Reduction in Rheumatoid Arthritis Patients on EtoBox?

Smoking Cessation Is Associated with Lower Disease Activity and Predicts Cardiovascular Risk Reduction in Rheumatoid Arthritis Patients by Ida K Roelsgaard; Eirik Ikdahl; Silvia Rollefstad; Grunde Wibetoe; Bente A Esbensen; George D Kitas; Piet van Riel; Sherine Gabriel; Tore K Kvien; Karen Douglas; Solveig Wållberg-Jonsson; Solbritt Rantapää Dahlqvist; George Karpouzas; Patrick H Dessein; Linda Tsang; Hani El-Gabalawy; Carol A Hitchon; Virginia Pascual-Ramos; Irazú Contreras-Yáñez; Petros P Sfikakis; Miguel A González-Gay; Cynthia S Crowson; Anne Grete Semb is a Medicine article available to read on EtoBox.

What is Smoking Cessation Is Associated with Lower Disease Activity and Predicts Cardiovascular Risk Reduction in Rheumatoid Arthritis Patients about?

## Abstract ## Objectives Smoking is a major risk factor for the development of both cardiovascular disease (CVD) and RA and may cause attenuated responses to anti-rheumatic treatments. Our aim was to compare disease activity, CVD risk factors and CVD event rates across smoking status in RA patients. ## Methods Disease characteristics, CVD risk factors and relevant medications were recorded in RA patients without prior CVD from 10 countries (Norway, UK, Netherlands, USA, Sweden, Greece, South Africa, Spain, Canada and Mexico). Information on CVD events was collected. Adjusted analysis of variance, logistic regression and Cox models were applied to compare RA disease activity (DAS28), CVD risk factors and event rates across categories of smoking status. ## Results Of the 3311 RA patients (1012 former, 887 current and 1412 never smokers), 235 experienced CVD events during a median follow-up of 3.5 years (interquartile range 2.5–6.1). At enrolment, current smokers were more likely to have moderate or high disease activity compared with former and never smokers (__P__ < 0.001 for both). There was a gradient of worsening CVD risk factor profiles (lipoproteins and blood pressure) from ne

Who reads Smoking Cessation Is Associated with Lower Disease Activity and Predicts Cardiovascular Risk Reduction in Rheumatoid Arthritis Patients?

Author

Ida K Roelsgaard; Eirik Ikdahl; Silvia Rollefstad; Grunde Wibetoe; Bente A Esbensen; George D Kitas; Piet van Riel; Sherine Gabriel; Tore K Kvien; Karen Douglas; Solveig Wållberg-Jonsson; Solbritt Rantapää Dahlqvist; George Karpouzas; Patrick H Dessein; Linda Tsang; Hani El-Gabalawy; Carol A Hitchon; Virginia Pascual-Ramos; Irazú Contreras-Yáñez; Petros P Sfikakis; Miguel A González-Gay; Cynthia S Crowson; Anne Grete Semb

Published

2019

Language

EN

Field

Medicine (Health Sciences)