Can I read Evaluation of Pre-analytical, Demographic, Behavioural and Metabolic Variables on Fibrinolysis and Haemostasis Activation Markers Utilised to Assess Hypercoagulability on EtoBox?

Evaluation of Pre-analytical, Demographic, Behavioural and Metabolic Variables on Fibrinolysis and Haemostasis Activation Markers Utilised to Assess Hypercoagulability by Mojca Stegnar; Tjaša Vižintin Cuderman; Mojca Božič is a Medicine article available to read on EtoBox.

What is Evaluation of Pre-analytical, Demographic, Behavioural and Metabolic Variables on Fibrinolysis and Haemostasis Activation Markers Utilised to Assess Hypercoagulability about?

## Background: Measurement of some haemostatic factors and products formed during activation of haemostasis seems to be promising in the determination of hypercoagulability. ## Methods: The fibrinolytic variables euglobulin clot lysis time, tissue-type plasminogen activator, plasminogen activator inhibitor-1 and the haemostasis activation markers prothrombin fragment 1+2, thrombin-antithrombin complex and d-dimer were determined in 101 apparently healthy men and women aged 20-92 years (58+/-18 years, mean+/-sd) to establish variability due to several demographic, behavioural and metabolic factors. ## Results: None of the fibrinolytic variables were affected by smoking, while tissue-type plasminogen activator antigen was significantly lower in women compared to men. multiple regression analysis revealed several independent associations between tissue-type plasminogen activator, plasminogen activator inhibitor, body mass index and lipid levels, describing up to 40% of the variance in fibrinolytic variables. for haemostasis activation markers, no gender difference or effect of smoking was observed. only d-dimer was independently associated with age. the haemostasis activation markers

Who reads Evaluation of Pre-analytical, Demographic, Behavioural and Metabolic Variables on Fibrinolysis and Haemostasis Activation Markers Utilised to Assess Hypercoagulability?

Author

Mojca Stegnar; Tjaša Vižintin Cuderman; Mojca Božič

Publisher

Walter de Gruyter GmbH & Co. KG; Walter de Gruyter GmbH (ISSN 1434-6621)

Published

2007

Language

EN

Field

Medicine (Health Sciences)