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High Throughput Solubility in Drug Discovery by Lia Rytel is a document available to read on EtoBox.

What is High Throughput Solubility in Drug Discovery about?

The document discusses the importance of high throughput solubility screens in drug discovery, emphasizing the need to address biopharmaceutical properties to reduce drug attrition rates. It outlines various methods for measuring solubility, including thermodynamic and kinetic approaches, and highlights the significance of using DMSO stocks for solubility testing. The review concludes that both kinetic and thermodynamic measurements are essential in understanding the solubility behavior of compounds during

Author

Lia Rytel

Language

EN