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Can I read Uncertainties − Discrepancies in Immunology on EtoBox?
Uncertainties − Discrepancies in Immunology by Rolf M. Zinkernagel is a Immunology and Microbiology article available to read on EtoBox.
What is Uncertainties − Discrepancies in Immunology about?
**Summary:** The many immunological observations and results from __in‐vitro__ or __in‐vivo__ experiments vary, and their interpretations differ enormously. A major problem is that within a normal distribution of biological phenomena, which are measurable with many methods, virtually anything is possible. Within a coevolutionary context, the definition of biologically relevant thresholds is an important key to improve our understanding of weaknesses and strengths of the immune system. This review is a personal view, comparing textbook rules and experiments using model antigens with observations on immunity against infections or tumors to critically evaluate our perception and understanding of specificity, affinity maturation, antigen presentation, selection of the class of the immune response, immunological memory and protective immunity, positive selection of T cells and self/nonself discrimination.
Who reads Uncertainties − Discrepancies in Immunology?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Rolf M. Zinkernagel
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0105-2896)
- Published
- 2002
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)