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What is Understanding Progressive Ossifying Fibrodysplasia about?

Progressive ossifying fibrodysplasia (POF) is a rare inherited autosomal dominant disease that causes connective tissues like tendons, ligaments and muscles to slowly turn into bone over time, forming an extra skeleton. It usually appears in children within the first 10 years of life and causes increasing loss of mobility as the extra bone formation progresses. Most people with POF have a life expectancy around 40 years old, as bone growth can restrict breathing by fixing the rib cage. The best known case w

Author

Valentina Patiño

Language

EN