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Can I read Repair of Acetone‐ and Sodium Lauryl Sulphate‐damaged Human Skin Barrier Function Using Topically Applied Emulsions Containing Barrier Lipids on EtoBox?
Repair of Acetone‐ and Sodium Lauryl Sulphate‐damaged Human Skin Barrier Function Using Topically Applied Emulsions Containing Barrier Lipids by K De Paepe; D Roseeuw; V Rogiers is a Medicine article available to read on EtoBox.
What is Repair of Acetone‐ and Sodium Lauryl Sulphate‐damaged Human Skin Barrier Function Using Topically Applied Emulsions Containing Barrier Lipids about?
## ABSTRACT **Background** It is generally acknowledged that well‐formulated moisturizing skin care products can restore disturbed barrier function that can be assessed by transepidermal water loss (TEWL) measurements. When ceramides and/or other barrier lipids are incorporated, it is, however, not always clearly demonstrated which ingredients of the formulation exert the beneficial effects. **Objectives** In this study the effects of topically applied ceramide‐containing mixtures on the barrier repair of sodium lauryl sulphate (SLS)‐ and acetone‐induced skin damage have been studied in human volunteers. TEWL and stratum corneum hydration measurements were carried out. The emulsions applied contained either a mixture of two types of ceramides, CerIII and CerIIIB (emulsion 1) or a complete mixture of ceramides III, IIIB and VI together with phytosphingosine, cholesterol and the free fatty acid linoleic acid (emulsion 2). **Results** After SLS damage, it was observed that barrier recovery was significantly accelerated by topical application (14 days, 2 ×/d) of emulsion 2 compared with the results obtained with emulsion 1. Corneometrical results were not relevant due to the occurrence
Who reads Repair of Acetone‐ and Sodium Lauryl Sulphate‐damaged Human Skin Barrier Function Using Topically Applied Emulsions Containing Barrier Lipids?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- K De Paepe; D Roseeuw; V Rogiers
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Wiley-Blackwell; Wiley (ISSN 0926-9959)
- Published
- 2002
- Language
- EN
- Field
- Medicine (Health Sciences)